Back to Blog
Meow match 1375/30/2023 ![]() ![]() Excessive intake of mephedrone leads to acute intoxication, displaying the clinical features of acute sympathomimetic toxidrome ( Wood et al., 2010a, b ) this has been linked to an increasing number of fatalities in European countries as reported recently ( Gustavsson and Escher, 2009 Dickson et al., 2010 Winstock et al., 2010a Lusthof et al., 2011). However, mephedrone is associated with a high risk of triggering repetitive and uncontrolled drug intake subsequent to its initial administration. A recent web-based survey from 1006 responders revealed that mephedrone users consider its effects best compared with those of MDMA ( Carhart-Harris et al., 2011). The users of mephedrone have described its psychomimetic effects being comparable to amphetamine, cocaine and 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) causing euphoria, elevated mood, stimulation, enhanced appreciation for music, decreased hostility, improved mental function and mild sexual stimulation ( Europol–EMCDDA, 2010). However, the unified international legislation and control of mephedrone as a substance of abuse is still missing. ![]() During the last 2 years, mephedrone has been banned in most of the EU countries. Recently, mephedrone has gained growing popularity as a ‘designer drug’ or a ‘research compound’ offered for sale under various names via Internet sites, head shops and recently, by street dealers ( Schifano et al., 2011 Winstock et al., 2010a, b 2011 ). Mephedrone (1-(4-methylphenyl)-2-methylaminopropan-1-one, 4-methylmethcathinone, 4-MMC) is a substituted phenethylamine, structurally a cathinone derivative that possesses powerful psychostimulant, entactogenic and hallucinogenic effects (see Europol–EMCDDA, 2010 Schifano et al., 2011). ![]()
0 Comments
Read More
Leave a Reply. |